D-Aspartic Acid: What Is It? What Are The Health Benefits

What is D-Aspartic Acid (DAA Supplement)? D-Aspartic Acid is an..

D-Aspartic Acid: What Is It? What Are The Health Benefits

What is D-Aspartic Acid (DAA Supplement)?

D-Aspartic Acid is an alpha amino acid found in a variety of foods like lunch meat, avocados, sprouts, and molasses. Aspartic acid is one of the amino acids that build protein used in the structure of the human body. It is predominantly found the pituitary gland and testes where it is produced via D-Aspartate racemase. 

There is also evidence that D-Aspartic Acid is important in human neurotransmission and is especially important for sight. Studies of embryos also suggest that D-Aspartic Acid is integral in the development of the nervous system as a whole. 

Science on the matter points to Aspartic acid as an important nutrient in the reproductive process, most likely because it works in the biosynthesis of sex hormones, or because it helps as a neuromodulator.

The D-Aspartic Acid form of Aspartic acid is an effective NMDA agonist which points to its importance in the brain. NMDA receptors are vital to almost all brain function including memory and learning.

While D-Aspartic Acid is available in food and is synthesized in the body, there is some evidence that additional supplementation can create desirable effects.

D Aspartic Acid Benefits

There’s a reason why we’re seeing D-AA in more and more testosterone boosters, and that reason is because there’s been quite a bit of scientific research and evidence pointing to the fact that DAA is quite effective at boosting testosterone.

Especially Effective For Men With Low T Levels

It looks like D aspartic acid is most effective in men that have lower levels of testosterone to begin vs. men that have normal healthy levels of T flowing through their body.

This study was conducted on two sets of men with healthy testosterone levels. One set of men were given 3g of D aspartic daily and the other group was given none. Both groups were given a 28-day weight lifting routine.

The results of test was that both groups showed significant improvement in their strength and muscle mass, however, they did not see any increase in the testosterone levels of the group that had taken D aspartic acid. (study)

DAA Increases Luteinizing Hormone

DAA has been shown to increase luteinizing hormones, which are the precursors to increasing testosterone. (study)

When luteinizing hormones (LH) are increased it sends a signal to the testes to produce more testosterone.

This study showed that D-Aspartic Acid can increase luteinizing hormone and testosterone by over 45% in as little as 13 days​ (study)


There appears to be some evidence that D-AA increases the fertility of men. There was one study in particular that noted that a group of men went from 0 conceptions to 26.6% reporting conceptions over a 90-day period of time supplementing with D aspartic acid.

Seminal Motility

Seminal motility has been shown to increase 50%-100% in men who are supplementing with D aspartic acid.

Sperm Count

Men supplementing with DAA have been shown to have an increase of sperm between 50% – 100%.

Cascading Benefits Of Increased Testosterone Levels

Since D aspartic acid is shown to ultimately increase testosterone levels, then you can expect all the secondary benefits that come along with healthy T levels:

  • Increased lean muscle
  • Reduced belly fat
  • Increased sex drive and improved sexual performance
  • More energy and stamina
  • More mental focus and clarity
  • Better overall mood and outlook
  • Stronger bone density
  • Better overall heart health​


Once you really examine D-Aspartic Acid closely and fully comprehend how powerful it is.

Possible side effects of DAA supplementation in males

As was discussed in the preamble, the good thing about DAA is that it presents a natural route to increase endogenous production of the hormones discussed herein. This is to say that you’re avoiding use of potentially harmful pharmaceutical compounds like anabolic steroids and prohormones, which can significantly affect your endocrine system when taken in large doses and for excessive periods of time.

That being said, there are still a few side effects that could arise from the use of DAA since it may elevate levels of the aforementioned hormones and other metabolites:

  • Increased dihydrotestosterone (DHT) levels which may cause hair loss and acne
  • Increased estrogen levels (due to aromatization of testosterone) which may cause bloating, gynecomastia, prostate issues, and inhibit libido. However, it should be noted that elevated estrogen side effects will be rare, if nonexistent, if you’re cycling your use of DAA as is recommended in this guide


How to take DAA

  • It is best to cycle your use of DAA in a 2-3 week “on” period followed by 1-2 weeks “off” and then repeating the cycle
  • Take your dose of DAA daily, mixed in liquid (if powder form), and with or without food
  • Split your dose into morning and evening doses if you are taking 5+ grams per day (see dosing recommendations below)


Recommended Dosing

  • Start with the lower limit of 3g per day and assess your tolerance/results after one cycle
  • It is suggested that a maximum dose of DAA be limited to 20 grams per day (which is actually quite high for most individuals)
  • Most individuals will see a good response with 5-10 grams per day.

Daniel Messer, RNutr, CPT

We eat clean, are always motivated and helpout beginners in need. We sell guides on Cutting, Bulking and Muscle Building. Checkout our website!

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